Susan Elizabeth Kolb The FDA partially funded a study published in the Journal of Rheumatology that found that women with ruptured implants had a higher risk of fibromyalgia. Last time I looked this study was still up on the FDA website despite the FDA and the plastic surgery society saying that only local complications occur from defective breast implants. Silicone is a known adjuvant so increased allergic reactions are common. One study (presented at a medical meeting) showed that 100% of women with defective breast implants had Candidiasis (fatigue, muscle aches and mental clouding) and that has been my clinical experience in treating over 2000 women who are ill. Other co infections occur such as viral, intracellular infection, fungal, and bacterial around infected foreign bodies of silicone in the lymphatic system. The risk of cancer is increased as shown in the peer reviewed literature as well as suicide as the ill women are not taken care of by the current medical system. Certain HLA types become very ill with autoimmune disease early after being exposed to any silicone and 25% of the population with saline implants is at risk for fibromyalgia from mold biotoxin disease if the implants become contaminated. ALCL lymphoma can occur with textured implants due to chemical toxicity and mold biotoxins which are known carcinogens. The chemical list provided by Dow Corning for the court shows a long list of chemicals many of which are neurotoxins and carcinogens that cause problems once the implants start to leak. Dow Corning engineering data shows that the Silastic shells start to leak at 8 years and clinically this is true in my practice in that most patients with detoxification defects (30% of the population) become ill in the 8 to 10 year time frame. Others become ill after chest wall trauma including a rough mammogram, car accident or direct trauma. Many women develop Raynaud's syndrome from the methyl ethyl ketone that comes out of the shell that depletes arginine and nitric oxide. It is reversible with chemical detox (hand baths) and supplements that restore nitric oxide. I wrote a book that I am not allowed to mention on Real Self that has many peer reviewed references from rheumatology, toxicology, pathology, neurology, cardiology, and other medical journals. The foreign medical literature also has articles about systemic illness in women with silicone implants. It is my experience that women with defective breast implants that do not have total capsulectomy, removal of silicone laden axillary lymph nodes, antifungals, treatment of coinfections, and detoxification do not do well and are at increased risk of cancer, suicide, infection, and a host of autoimmune and fibromyalgia and chronic pain problems. Oddly enough, with all of this evidence, chances are that most plastic surgeons will answer your question saying that only local chest wall complications have been found. American medicine has many politically incorrect diseases including silicone toxicity, mold biotoxin illness, intracellular infections, and chemical toxicity in general. In my experience, patients with defective silicone illness may have all of these diseases, so it is no surprise that there is so little help for the women who are ill.